| ncRNA name | AEG-1 siRNA |
| ncRNA Category | siRNA |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | RB cell lines Y79 and SO-RB50 |
| Methods | transfection, qRT-PCR, Western blot, immunohistochemical staining, MTT assay, Annexin V-APC staining, flow cytometry |
| Expression pattern | associated |
| Functional description | Expression of AEG-1 was associated with RB, in histological slides of patients and in cell culture experiments. Lentivirus transfection induced knockdown of AEG-1 had a tumor suppressive effect, potentially by tumor cell apoptosis induction through inhibition of ERK. |
| PubMed ID | 26894431 |
| Year | 2016 |
| Title | Lentivirus-Mediated Knockdown of Astrocyte Elevated Gene-1 Inhibits Growth and Induces Apoptosis through MAPK Pathways in Human Retinoblastoma Cells. |
| Drug-related ncRNA | NO |
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